Compile Data Set for Download or QSAR
maximum 50k data
Found 2869 of ic50 data for polymerid = 2871,4904
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50513279(CHEMBL4554455)
Affinity DataIC50:  0.0700nMAssay Description:Inhibition of human recombinant N-terminal His-tagged FAK (393 to 698 residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 Gl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50206389(CHEMBL3939307)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of VEGFR3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50590475(CHEMBL5170906)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of recombinant human FAK (393 to 698 residues) using poly (4:1 Glu, Tyr) peptide as substrate incubated for 60 mins in presence of ATP by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM25117(AG-013736 | AXITINIB | N-methyl-2-({3-[(E)-2-(pyri...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of VEGFR3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM25117(AG-013736 | AXITINIB | N-methyl-2-({3-[(E)-2-(pyri...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of VEGFR3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50590490(CHEMBL5198068)
Affinity DataIC50:  0.108nMAssay Description:Inhibition of recombinant human FAK (393 to 698 residues) using poly (4:1 Glu, Tyr) peptide as substrate incubated for 60 mins in presence of ATP by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50595124(CHEBI:49960 | Caprelsa | GNF-PF-2188 | NSC-744325 ...)
Affinity DataIC50:  0.110nMAssay Description:Inhibition of VEGFR3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50590479(CHEMBL5196177)
Affinity DataIC50:  0.117nMAssay Description:Inhibition of recombinant human FAK (393 to 698 residues) using poly (4:1 Glu, Tyr) peptide as substrate incubated for 60 mins in presence of ATP by ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50590489(CHEMBL5176233)
Affinity DataIC50:  0.124nMAssay Description:Inhibition of recombinant human FAK (393 to 698 residues) using poly (4:1 Glu, Tyr) peptide as substrate incubated for 60 mins in presence of ATP by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50590488(CHEMBL5206909)
Affinity DataIC50:  0.153nMAssay Description:Inhibition of recombinant human FAK (393 to 698 residues) using poly (4:1 Glu, Tyr) peptide as substrate incubated for 60 mins in presence of ATP by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50590483(CHEMBL5187385)
Affinity DataIC50:  0.161nMAssay Description:Inhibition of recombinant human FAK (393 to 698 residues) using poly (4:1 Glu, Tyr) peptide as substrate incubated for 60 mins in presence of ATP by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50590484(CHEMBL5190968)
Affinity DataIC50:  0.192nMAssay Description:Inhibition of recombinant human FAK (393 to 698 residues) using poly (4:1 Glu, Tyr) peptide as substrate incubated for 60 mins in presence of ATP by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50590485(CHEMBL5177776)
Affinity DataIC50:  0.194nMAssay Description:Inhibition of recombinant human FAK (393 to 698 residues) using poly (4:1 Glu, Tyr) peptide as substrate incubated for 60 mins in presence of ATP by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50362065(CHEMBL1940109)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of VEGFR3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50590474(CHEMBL5176990)
Affinity DataIC50:  0.213nMAssay Description:Inhibition of recombinant human FAK (393 to 698 residues) using poly (4:1 Glu, Tyr) peptide as substrate incubated for 60 mins in presence of ATP by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50331095(CHEMBL1289494 | Tivozanib | US10464902, Tivozanib)
Affinity DataIC50:  0.240nMAssay Description:Inhibition of VEGFR3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50590477(CHEMBL5204729)
Affinity DataIC50:  0.275nMAssay Description:Inhibition of recombinant human FAK (393 to 698 residues) using poly (4:1 Glu, Tyr) peptide as substrate incubated for 60 mins in presence of ATP by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50590482(CHEMBL5186801)
Affinity DataIC50:  0.296nMAssay Description:Inhibition of recombinant human FAK (393 to 698 residues) using poly (4:1 Glu, Tyr) peptide as substrate incubated for 60 mins in presence of ATP by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM155552(US9012461, 28)
Affinity DataIC50:  0.300nMpH: 7.4Assay Description:A biotin labeled peptide is used as substrate (amino acid sequence: Biotin-Glu-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2)1S...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50590487(CHEMBL5199835)
Affinity DataIC50:  0.315nMAssay Description:Inhibition of recombinant human FAK (393 to 698 residues) using poly (4:1 Glu, Tyr) peptide as substrate incubated for 60 mins in presence of ATP by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50590476(CHEMBL5178369)
Affinity DataIC50:  0.315nMAssay Description:Inhibition of recombinant human FAK (393 to 698 residues) using poly (4:1 Glu, Tyr) peptide as substrate incubated for 60 mins in presence of ATP by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM155547(US9012461, 23)
Affinity DataIC50:  0.390nMpH: 7.4Assay Description:A biotin labeled peptide is used as substrate (amino acid sequence: Biotin-Glu-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2)1S...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50362064(CHEMBL1940108)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of VEGFR3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50568532(CHEMBL4742157)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of FAK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50336457((3S,5Z,8S,9R,11E)-8,9,16-trihydroxy-14-methoxy-3-m...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human recombinant VEGFR3 in cell free system after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM418817(N-methyl-4-({4-[({3- [methyl(methylsulfonyl)amino]...)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of recombinant FAK (unknown origin) by radiometric kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50246239(CHEMBL487229 | N-methyl-N-(2-((2-(1-oxoisoindolin-...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of GST-tagged FAK (unknown origin) assessed as inhibition of poly-Glu-Tyr phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50592745(CHEMBL5188373)
Affinity DataIC50:  0.510nMAssay Description:Inhibition of FAK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50207359(CHEMBL3892377)
Affinity DataIC50:  0.510nMAssay Description:Inhibition of NH2-terminal His6-tagged FAK kinase domain (410 to 689 residues) (unknown origin) expressed in baculovirus infected sf9 cells using p(G...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50207351(CHEMBL3965256)
Affinity DataIC50:  0.510nMAssay Description:Inhibition of NH2-terminal His6-tagged FAK kinase domain (410 to 689 residues) (unknown origin) expressed in baculovirus infected sf9 cells using p(G...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50590486(CHEMBL5177168)
Affinity DataIC50:  0.514nMAssay Description:Inhibition of recombinant human FAK (393 to 698 residues) using poly (4:1 Glu, Tyr) peptide as substrate incubated for 60 mins in presence of ATP by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50590473(CHEMBL5192604)
Affinity DataIC50:  0.579nMAssay Description:Inhibition of recombinant human FAK (393 to 698 residues) using poly (4:1 Glu, Tyr) peptide as substrate incubated for 60 mins in presence of ATP by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM418609(N-methyl-4-({4-[({2- [methyl(methylsulfonyl)amino]...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human FAKMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50554439(CHEMBL4752642)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of FAK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM418817(N-methyl-4-({4-[({3- [methyl(methylsulfonyl)amino]...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human recombinant FAKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM155537(US9012461, 13)
Affinity DataIC50:  0.600nMpH: 7.4Assay Description:A biotin labeled peptide is used as substrate (amino acid sequence: Biotin-Glu-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2)1S...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50554439(CHEMBL4752642)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of recombinant human N-terminal His-tagged FAK (393 to 698 residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 Gl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM418817(N-methyl-4-({4-[({3- [methyl(methylsulfonyl)amino]...)
Affinity DataIC50:  0.630nMAssay Description:Inhibition of FAK (unknown origin) using Fluorescein-Poly GAT as substrate incubated for 30 mins and measured after 60 mins by Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human FLT4 using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)
Affinity DataIC50:  0.730nMAssay Description:Inhibition of human VEGFR3 using poly[Glu:Tyr] (4:1) substrate and [gamma-33P]-ATP by radiometric biochemical kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM155548(US9012461, 24)
Affinity DataIC50:  0.770nMpH: 7.4Assay Description:A biotin labeled peptide is used as substrate (amino acid sequence: Biotin-Glu-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2)1S...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50321892((Z)-5-{6-[3-(4-Methoxyphenyl)-ureido]-2-oxo-1,2-di...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of VEGFR3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM155544(US9012461, 20)
Affinity DataIC50:  0.810nMpH: 7.4Assay Description:A biotin labeled peptide is used as substrate (amino acid sequence: Biotin-Glu-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2)1S...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of FLT4 (unknown origin) incubated for 1 hr by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50246286(CHEMBL488247 | N-methyl-N-(2-((2-(4-(methylsulfony...)
Affinity DataIC50:  0.940nMAssay Description:Inhibition of GST-tagged FAK (unknown origin) assessed as inhibition of poly-Glu-Tyr phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50590481(CHEMBL5180558)
Affinity DataIC50:  0.976nMAssay Description:Inhibition of recombinant human FAK (393 to 698 residues) using poly (4:1 Glu, Tyr) peptide as substrate incubated for 60 mins in presence of ATP by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM134162(US8846689, 164)
Affinity DataIC50:  1nMpH: 7.5Assay Description:This test uses active PTK2 enzyme (Invitrogen Code PV3832) and poly-Glu-Tyr (4:1, Sigma P-0275) as the kinase substrate. The kinase activity is detec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM134164(US8846689, 166)
Affinity DataIC50:  1nMpH: 7.5Assay Description:This test uses active PTK2 enzyme (Invitrogen Code PV3832) and poly-Glu-Tyr (4:1, Sigma P-0275) as the kinase substrate. The kinase activity is detec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM134166(US8846689, 168)
Affinity DataIC50:  1nMpH: 7.5Assay Description:This test uses active PTK2 enzyme (Invitrogen Code PV3832) and poly-Glu-Tyr (4:1, Sigma P-0275) as the kinase substrate. The kinase activity is detec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM134167(US8846689, 169)
Affinity DataIC50:  1nMpH: 7.5Assay Description:This test uses active PTK2 enzyme (Invitrogen Code PV3832) and poly-Glu-Tyr (4:1, Sigma P-0275) as the kinase substrate. The kinase activity is detec...More data for this Ligand-Target Pair
In DepthDetails US Patent
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